Adipose Derived Stem Cell Therapy in the Treatment of Canine Degenerative Joint Disease Secondary to Conformational Abnormalities.

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Effect of adipose-derived nucleated cell fractions on tendon repair in horses with collagenase-induced tendinitis
Alan J. Nixon, BVSc, MS; Linda A. Dahlgren, DVM, PhD; Jennifer L. Haupt, BS; Amy E. Yeager, DVM;Daniel L. Ward, PhD

Conclusions and Clinical Relevance—ADNC injection improved tendon organization in
treated tendons. Although biochemical and molecular differences were less profound, tendons
appeared architecturally improved after ADNC injection, which was corroborated by
improved tendon COMP expression. Use of ADNC in horses with tendinitis appears warranted.
(Am J Vet Res 2008;69:928–937)
AJVR, Vol 69, No. 7, July 2008

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Adipose-derived stem cell: a better stem cell than BMSC
Zhu Y, Liu T, Song K, Fan X, Ma X, Cui Z.

To further study the proliferation and multi-differentiation potentials of adipose-derived stem cells (ADSCs), the cells were isolated with improved methods and their growth curves were achieved with cck-8. Surface protein expression was analyzed by flow cytometry to characterize the cell phenotype. The multi-lineage potential of ADSCs was testified by differentiating cells with adipogenic, chondrogenic, osteogenic, and myogenic inducers.

Cell Biochem Funct. 2008 Aug;26(6):664-75

Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, China.

Enhanced Suspensory Ligament Healing in 100 Horses by Stem Cells and Other Bone Marrow Components
Douglas J. Herthel, DVM

Suspensory ligament injuries are challenging because healing is slow and reinjuries are common. Healing requires growth factors that stimulate angiogenesis, mitogenesis, and matrix formation. Bone marrow contains growth factors, cells, and fibrinogen, which facilitate healing of damaged tissues. In 100 horses with ligament damage, bone marrow seems to enhance healing.
Author’s address: Alamo Pintado Equine Medical Center, Los Olivos, CA 93441. © 2001 AAEP.
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Pferdeheilkunde 22 (2006) 5 (September/Oktober) 559-563

Mesenchymal stem cell treatment of suspensory ligament branch desmitis: post mortem findings in a 10 year old Russion Warmblood gelding - a case report
David R. Mountford, Roger K. W. Smith and Janet C. Patterson-Kane

VetCell BioScience Limited, London BioScience Innovation Centre, Department of Veterinary Clinical Sciences, The Royal Veterinary College and Department ofPathology and Infectious Diseases, The Royal Veterinary College, London, UK ...